Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008].

potassium voltage-gated channel subfamily H member 7MIM:608169Ensembl:ENSG00000184611HGNC:HGNC:18863PA387232q24.2

GO terms in KCNH7

Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0034765regulation of ion transmembrane transport
BPIBAGO:0042391regulation of membrane potential
BPIBAGO:0071805potassium ion transmembrane transport
BPIEAGO:0071805potassium ion transmembrane transport
CCTASGO:0005886plasma membrane
CCIBAGO:0005887integral component of plasma membrane
MFIBAGO:0005249voltage-gated potassium channel activity

Gene expression in normal tissue: KCNH7

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in KCNH7

DatabasePathway IDPathway Des.
reactomeR-HSA-112316Neuronal System
reactomeR-HSA-1296071Potassium Channels
reactomeR-HSA-1296072Voltage gated Potassium channels

Gene-Drug: Aster Plot

Drug IDDrug NameModel Num.

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KCNH7