MED30
Summary: The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:610237 Ensembl IDEnsembl:ENSG00000164758 HGNC IDHGNC:HGNC:23032 PHARMGKB IDPA162395656 Map Location8q24.11 | |||||
Gene Categories:
TRANSCRIPTION FACTOR BINDINGGO terms in MED30
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0006367 | transcription initiation from RNA polymerase II promoter |
| BP | IDA | GO:0006367 | transcription initiation from RNA polymerase II promoter |
| BP | TAS | GO:0006367 | transcription initiation from RNA polymerase II promoter |
| BP | IEA | GO:0016567 | protein ubiquitination |
| BP | IEA | GO:0019827 | stem cell population maintenance |
| BP | IDA | GO:0030518 | intracellular steroid hormone receptor signaling pathway |
Gene expression in normal tissue: MED30
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MED30
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04919 | Thyroid hormone signaling pathway - Homo sapiens (human) |
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1989781 | PPARA activates gene expression |
| reactome | R-HSA-212436 | Generic Transcription Pathway |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD68 | Paclitaxel | 2 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MED30
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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