INA
Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| internexin neuronal intermediate filament protein alpha | MIM:605338 | Ensembl:ENSG00000148798 | HGNC:HGNC:6057 | PA29867 | 10q24.33 |
GO terms in INA
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | HDA | GO:0005615 | extracellular space |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IEA | GO:0005883 | neurofilament |
| CC | IDA | GO:0031965 | nuclear membrane |
| CC | IDA | GO:0036464 | cytoplasmic ribonucleoprotein granule |
| CC | IEA | GO:0043209 | myelin sheath |
| CC | IDA | GO:0045111 | intermediate filament cytoskeleton |
| BP | HEP | GO:0021762 | substantia nigra development |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | IEA | GO:0060052 | neurofilament cytoskeleton organization |
| BP | IEA | GO:1990830 | cellular response to leukemia inhibitory factor |
| MF | TAS | GO:0005200 | structural constituent of cytoskeleton |
Gene expression in normal tissue: INA
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in INA
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in INA
CLASSFICATION
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