INA
Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:605338 Ensembl IDEnsembl:ENSG00000148798 HGNC IDHGNC:HGNC:6057 PHARMGKB IDPA29867 Map Location10q24.33 | |||||
GO terms in INA
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | HDA | GO:0005615 | extracellular space |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IEA | GO:0005883 | neurofilament |
| CC | IDA | GO:0031965 | nuclear membrane |
| CC | IDA | GO:0036464 | cytoplasmic ribonucleoprotein granule |
| CC | IEA | GO:0043209 | myelin sheath |
Gene expression in normal tissue: INA
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in INA
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in INA
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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