SLC16A5

Summary: This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namesolute carrier family 16 member 5
OMIM IDMIM:603879
Ensembl IDEnsembl:ENSG00000170190
HGNC IDHGNC:HGNC:10926
PHARMGKB IDPA35817
Map Location17q25.1

GO terms in SLC16A5


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0005215 transporter activity
MF IBA GO:0008028 monocarboxylic acid transmembrane transporter activity
MF IEA GO:0015293 symporter activity
BP IBA GO:0015718 monocarboxylic acid transport
BP IEA GO:0015718 monocarboxylic acid transport
BP IEA GO:0055085 transmembrane transport
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Gene expression in normal tissue: SLC16A5

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

Pathways in SLC16A5


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SLC16A5

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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