GPR37L1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| G protein-coupled receptor 37 like 1 | MIM:617630 | Ensembl:ENSG00000170075 | HGNC:HGNC:14923 | PA28883 | 1q32.1 |
GO terms in GPR37L1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005886 | plasma membrane |
| CC | NAS | GO:0016021 | integral component of membrane |
| CC | IDA | GO:0043235 | receptor complex |
| BP | TAS | GO:0007186 | G-protein coupled receptor signaling pathway |
| BP | IDA | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway |
| BP | IEA | GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation |
| BP | IDA | GO:0043410 | positive regulation of MAPK cascade |
| BP | IEA | GO:0045665 | negative regulation of neuron differentiation |
| BP | IEA | GO:0045879 | negative regulation of smoothened signaling pathway |
| BP | IEA | GO:0048712 | negative regulation of astrocyte differentiation |
| BP | ISS | GO:1903206 | negative regulation of hydrogen peroxide-induced cell death |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0008528 | G-protein coupled peptide receptor activity |
| MF | IDA | GO:0036505 | prosaposin receptor activity |
| MF | IPI | GO:0042277 | peptide binding |
Gene expression in normal tissue: GPR37L1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GPR37L1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-372790 | Signaling by GPCR |
| reactome | R-HSA-373076 | Class A/1 (Rhodopsin-like receptors) |
| reactome | R-HSA-375276 | Peptide ligand-binding receptors |
| reactome | R-HSA-388396 | GPCR downstream signalling |
| reactome | R-HSA-418594 | G alpha (i) signalling events |
| reactome | R-HSA-500792 | GPCR ligand binding |
| wikipathways | WP455 | GPCRs, Class A Rhodopsin-like |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GPR37L1
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.