GTPBP1
Summary: This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:602245 Ensembl IDEnsembl:ENSG00000100226 HGNC IDHGNC:HGNC:4669 PHARMGKB IDPA29057 Map Location22q13.1 | |||||
GO terms in GTPBP1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IBA | GO:0003746 | translation elongation factor activity |
| MF | ISS | GO:0003924 | GTPase activity |
| MF | IEA | GO:0005525 | GTP binding |
| CC | ISS | GO:0000177 | cytoplasmic exosome (RNase complex) |
| CC | ISS | GO:0005829 | cytosol |
Gene expression in normal tissue: GTPBP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GTPBP1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GTPBP1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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