GTPBP1
Summary: This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| GTP binding protein 1 | MIM:602245 | Ensembl:ENSG00000100226 | HGNC:HGNC:4669 | PA29057 | 22q13.1 |
GO terms in GTPBP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IBA | GO:0003746 | translation elongation factor activity |
| MF | ISS | GO:0003924 | GTPase activity |
| MF | IEA | GO:0005525 | GTP binding |
| CC | ISS | GO:0000177 | cytoplasmic exosome (RNase complex) |
| CC | ISS | GO:0005829 | cytosol |
| CC | HDA | GO:0016020 | membrane |
| BP | IBA | GO:0006414 | translational elongation |
| BP | TAS | GO:0006955 | immune response |
| BP | TAS | GO:0007165 | signal transduction |
| BP | ISS | GO:0046039 | GTP metabolic process |
| BP | ISS | GO:0061014 | positive regulation of mRNA catabolic process |
Gene expression in normal tissue: GTPBP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GTPBP1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GTPBP1
CLASSFICATION
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