IPO13
Summary: This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.[provided by RefSeq, Mar 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameimportin 13 OMIM IDMIM:610411 Ensembl IDEnsembl:ENSG00000117408 HGNC IDHGNC:HGNC:16853 PHARMGKB IDPA134981096 Map Location1p34.1 | |||||
Gene Categories:
TRANSPORTERGO terms in IPO13
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005737 | cytoplasm |
| BP | IBA | GO:0006606 | protein import into nucleus |
| BP | IDA | GO:0006606 | protein import into nucleus |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0008139 | nuclear localization sequence binding |
| MF | IEA | GO:0008536 | Ran GTPase binding |
Gene expression in normal tissue: IPO13
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in IPO13
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in IPO13
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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