CD69
Summary: This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
NameCD69 molecule OMIM IDMIM:107273 Ensembl IDEnsembl:ENSG00000110848 HGNC IDHGNC:HGNC:1694 PHARMGKB IDPA26233 Map Location12p13.31 | |||||
GO terms in CD69
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005887 | integral component of plasma membrane |
| CC | IEA | GO:0009897 | external side of plasma membrane |
| CC | IMP | GO:0032991 | protein-containing complex |
| BP | IEA | GO:0007165 | signal transduction |
| BP | IEA | GO:0035690 | cellular response to drug |
| MF | TAS | GO:0004888 | transmembrane signaling receptor activity |
Gene expression in normal tissue: CD69
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CD69
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP286 | IL-3 Signaling Pathway |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD90 | Bendamustine HCl | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CD69
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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