RAB11FIP3
Summary: Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:608738 Ensembl IDEnsembl:ENSG00000090565 HGNC IDHGNC:HGNC:17224 PHARMGKB IDPA134950896 Map Location16p13.3 | |||||
Gene Categories:
CELL SURFACEGO terms in RAB11FIP3
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0000910 | cytokinesis |
| BP | TAS | GO:0016192 | vesicle-mediated transport |
| BP | IBA | GO:0032456 | endocytic recycling |
| BP | IDA | GO:0032456 | endocytic recycling |
| BP | IMP | GO:0032465 | regulation of cytokinesis |
| BP | IDA | GO:0070164 | negative regulation of adiponectin secretion |
Gene expression in normal tissue: RAB11FIP3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RAB11FIP3
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1852241 | Organelle biogenesis and maintenance |
| reactome | R-HSA-5617833 | Cilium Assembly |
| reactome | R-HSA-5620916 | VxPx cargo-targeting to cilium |
| reactome | R-HSA-5620920 | Cargo trafficking to the periciliary membrane |
| pid | arf6downstreampathway | Arf6 downstream pathway |
| kegg | hsa04144 | Endocytosis - Homo sapiens (human) |
Showing 1 to 6 of 6 rows
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 2 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RAB11FIP3
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.