PCLAF
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| PCNA clamp associated factor | MIM:610696 | Ensembl:ENSG00000166803 | HGNC:HGNC:28961 | PA134974023 | 15q22.31 |
GO terms in PCLAF
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0003682 | chromatin binding |
| MF | IDA | GO:0003682 | chromatin binding |
| MF | IPI | GO:0005515 | protein binding |
| BP | IDA | GO:0006260 | DNA replication |
| BP | IDA | GO:0006974 | cellular response to DNA damage stimulus |
| BP | IMP | GO:0007098 | centrosome cycle |
| BP | IDA | GO:0009411 | response to UV |
| BP | IBA | GO:0019985 | translesion synthesis |
| BP | IMP | GO:0019985 | translesion synthesis |
| BP | TAS | GO:0019985 | translesion synthesis |
| BP | IMP | GO:0051726 | regulation of cell cycle |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005813 | centrosome |
| CC | IDA | GO:0048471 | perinuclear region of cytoplasm |
Gene expression in normal tissue: PCLAF
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PCLAF
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-110313 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| reactome | R-HSA-5656169 | Termination of translesion DNA synthesis |
| reactome | R-HSA-73893 | DNA Damage Bypass |
| reactome | R-HSA-73894 | DNA Repair |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PCLAF
CLASSFICATION
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