SPOCK2
Summary: This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:607988 Ensembl IDEnsembl:ENSG00000107742 HGNC IDHGNC:HGNC:13564 PHARMGKB IDPA128394560 Map Location10q22.1 | |||||
GO terms in SPOCK2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0005509 | calcium ion binding |
| MF | IDA | GO:0005509 | calcium ion binding |
| MF | IBA | GO:0005518 | collagen binding |
| MF | IEA | GO:0005539 | glycosaminoglycan binding |
| MF | TAS | GO:0008191 | metalloendopeptidase inhibitor activity |
| MF | IBA | GO:0050840 | extracellular matrix binding |
Gene expression in normal tissue: SPOCK2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SPOCK2
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD309 | 17AAG | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SPOCK2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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