SFI1
Summary:
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:612765 Ensembl IDEnsembl:ENSG00000198089 HGNC IDHGNC:HGNC:29064 PHARMGKB IDPA142670930 Map Location22q12.2 |
Gene Categories:
TUMOR SUPPRESSORGO terms in SFI1
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IPI | GO:0005515 | protein binding |
MF | IDA | GO:0019902 | phosphatase binding |
BP | TAS | GO:0000086 | G2/M transition of mitotic cell cycle |
BP | TAS | GO:0010389 | regulation of G2/M transition of mitotic cell cycle |
BP | IDA | GO:0010923 | negative regulation of phosphatase activity |
BP | TAS | GO:0097711 | ciliary basal body-plasma membrane docking |
Gene expression in normal tissue: SFI1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SFI1
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Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-1640170 | Cell Cycle |
reactome | R-HSA-1852241 | Organelle biogenesis and maintenance |
reactome | R-HSA-2565942 | Regulation of PLK1 Activity at G2/M Transition |
reactome | R-HSA-380259 | Loss of Nlp from mitotic centrosomes |
reactome | R-HSA-380270 | Recruitment of mitotic centrosome proteins and complexes |
reactome | R-HSA-380284 | Loss of proteins required for interphase microtubule organization from the centrosome |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in SFI1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |