SFI1


Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

Gene Categories:

TUMOR SUPPRESSOR

GO terms in SFI1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF IDA GO:0019902 phosphatase binding
BP TAS GO:0000086 G2/M transition of mitotic cell cycle
BP TAS GO:0010389 regulation of G2/M transition of mitotic cell cycle
BP IDA GO:0010923 negative regulation of phosphatase activity
BP TAS GO:0097711 ciliary basal body-plasma membrane docking
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Gene expression in normal tissue: SFI1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in SFI1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1640170 Cell Cycle
reactome R-HSA-1852241 Organelle biogenesis and maintenance
reactome R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition
reactome R-HSA-380259 Loss of Nlp from mitotic centrosomes
reactome R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
reactome R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SFI1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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