ADGRG6
Summary: This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| adhesion G protein-coupled receptor G6 | MIM:612243 | Ensembl:ENSG00000112414 | HGNC:HGNC:13841 | PA134878328 | 6q24.2 |
GO terms in ADGRG6
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0001965 | G-protein alpha-subunit binding |
| MF | IBA | GO:0004930 | G-protein coupled receptor activity |
| MF | IMP | GO:0004930 | G-protein coupled receptor activity |
| MF | ISS | GO:0004930 | G-protein coupled receptor activity |
| MF | ISS | GO:0005518 | collagen binding |
| MF | IBA | GO:0043236 | laminin binding |
| MF | ISS | GO:0043236 | laminin binding |
| MF | ISS | GO:0050840 | extracellular matrix binding |
| CC | IEA | GO:0005622 | intracellular |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | IBA | GO:0005887 | integral component of plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| BP | IEA | GO:0007005 | mitochondrion organization |
| BP | ISS | GO:0007166 | cell surface receptor signaling pathway |
| BP | ISS | GO:0007186 | G-protein coupled receptor signaling pathway |
| BP | IEA | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway |
| BP | IMP | GO:0014037 | Schwann cell differentiation |
| BP | IMP | GO:0019933 | cAMP-mediated signaling |
| BP | ISS | GO:0019933 | cAMP-mediated signaling |
| BP | IBA | GO:0022011 | myelination in peripheral nervous system |
| BP | ISS | GO:0022011 | myelination in peripheral nervous system |
| BP | IMP | GO:0042552 | myelination |
| BP | IBA | GO:0060347 | heart trabecula formation |
| BP | IEA | GO:0060347 | heart trabecula formation |
Gene expression in normal tissue: ADGRG6
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ADGRG6
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ADGRG6
CLASSFICATION
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