ARPP21


Summary: This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
cAMP regulated phosphoprotein 21MIM:605488Ensembl:ENSG00000172995HGNC:HGNC:16968PA1660489493p22.3

GO terms in ARPP21


Term TypeEvidence TypeGO Term IDGO Des.
CCNDGO:0005575cellular_component
CCIEAGO:0005737cytoplasm
BPNDGO:0008150biological_process
BPIEAGO:0034605cellular response to heat
MFNDGO:0003674molecular_function
MFIEAGO:0003676nucleic acid binding
MFIEAGO:0005516calmodulin binding

Gene expression in normal tissue: ARPP21

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ARPP21


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD30917AAG1
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ARPP21

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