ATF7IP


Summary: ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
activating transcription factor 7 interacting proteinMIM:613644Ensembl:ENSG00000171681HGNC:HGNC:20092PA13488946012p13.1

GO terms in ATF7IP


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0003714transcription corepressor activity
MFIPIGO:0005515protein binding
MFIEAGO:0016887ATPase activity
CCIDAGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCTASGO:0005654nucleoplasm
CCIEAGO:0005667transcription factor complex
CCIDAGO:0005829cytosol
CCIDAGO:0016604nuclear body
BPIEAGO:0000122negative regulation of transcription by RNA polymerase II
BPIDAGO:0006306DNA methylation
BPIEAGO:0006351transcription, DNA-templated
BPIEAGO:0016032viral process
BPIDAGO:0045892negative regulation of transcription, DNA-templated
BPIDAGO:0045893positive regulation of transcription, DNA-templated
BPIDAGO:0045898regulation of RNA polymerase II transcriptional preinitiation complex assembly

Gene expression in normal tissue: ATF7IP

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ATF7IP


DatabasePathway IDPathway Des.
reactomeR-HSA-3214841PKMTs methylate histone lysines
reactomeR-HSA-3247509Chromatin modifying enzymes
reactomeR-HSA-4839726Chromatin organization

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ATF7IP

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