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ATF7IP

Summary: ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
activating transcription factor 7 interacting protein	MIM:613644	Ensembl:ENSG00000171681	HGNC:HGNC:20092	PA134889460	12p13.1

Gene Categories:

TRANSCRIPTION FACTOR COMPLEX

GO terms in ATF7IP

Term Type	Evidence Type	GO Term ID	GO Des.
MF	IEA	GO:0003714	transcription corepressor activity
MF	IPI	GO:0005515	protein binding
MF	IEA	GO:0016887	ATPase activity
CC	IDA	GO:0005634	nucleus
CC	IDA	GO:0005654	nucleoplasm
CC	TAS	GO:0005654	nucleoplasm
CC	IEA	GO:0005667	transcription factor complex
CC	IDA	GO:0005829	cytosol
CC	IDA	GO:0016604	nuclear body
BP	IEA	GO:0000122	negative regulation of transcription by RNA polymerase II
BP	IDA	GO:0006306	DNA methylation
BP	IEA	GO:0006351	transcription, DNA-templated
BP	IEA	GO:0016032	viral process
BP	IDA	GO:0045892	negative regulation of transcription, DNA-templated
BP	IDA	GO:0045893	positive regulation of transcription, DNA-templated
BP	IDA	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly

Gene expression in normal tissue: ATF7IP

Select Project:

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ATF7IP

Database	Pathway ID	Pathway Des.
reactome	R-HSA-3214841	PKMTs methylate histone lysines
reactome	R-HSA-3247509	Chromatin modifying enzymes
reactome	R-HSA-4839726	Chromatin organization

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD353	PD0325901	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ATF7IP

SITE

DATATYPES

CLASSFICATION

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