ATG2B
Summary: This gene encodes a protein required for autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
autophagy related 2B | MIM:616226 | Ensembl:ENSG00000066739 | HGNC:HGNC:20187 | PA162377102 | 14q32.2 |
GO terms in ATG2B
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IBA | GO:0000407 | phagophore assembly site |
CC | IDA | GO:0005654 | nucleoplasm |
CC | IEA | GO:0005811 | lipid droplet |
CC | IBA | GO:0019898 | extrinsic component of membrane |
CC | IEA | GO:0034045 | phagophore assembly site membrane |
BP | IBA | GO:0000045 | autophagosome assembly |
BP | IBA | GO:0000422 | autophagy of mitochondrion |
BP | IBA | GO:0044804 | autophagy of nucleus |
Gene expression in normal tissue: ATG2B
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ATG2B
Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa04136 | Autophagy - other - Homo sapiens (human) |
kegg | hsa04140 | Autophagy - animal - Homo sapiens (human) |
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in ATG2B