BSN


Summary: Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
bassoon presynaptic cytomatrix proteinMIM:604020Ensembl:ENSG00000164061HGNC:HGNC:1117PA254343p21.31

Gene Categories:

CELL SURFACE

GO terms in BSN


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0046872metal ion binding
BPTASGO:0007268chemical synaptic transmission
BPIEAGO:0007416synapse assembly
BPIEAGO:0035418protein localization to synapse
BPIEAGO:0099526presynapse to nucleus signaling pathway
CCTASGO:0005634nucleus
CCIEAGO:0009986cell surface
CCIEAGO:0014069postsynaptic density
CCIEAGO:0030054cell junction
CCIEAGO:0030424axon
CCISSGO:0030425dendrite
CCIEAGO:0044306neuron projection terminus
CCISSGO:0048786presynaptic active zone
CCISSGO:0048788cytoskeleton of presynaptic active zone
CCTASGO:0048788cytoskeleton of presynaptic active zone
CCISSGO:0060076excitatory synapse

Gene expression in normal tissue: BSN

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in BSN


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD30917AAG1
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BSN

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