CALY
Summary: The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs. [provided by RefSeq, Jul 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
calcyon neuron specific vesicular protein | MIM:604647 | Ensembl:ENSG00000130643 | HGNC:HGNC:17938 | PA162380987 | 10q26.3 |
GO terms in CALY
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IEA | GO:0006897 | endocytosis |
BP | IEA | GO:0007212 | dopamine receptor signaling pathway |
BP | IBA | GO:0016197 | endosomal transport |
BP | IMP | GO:0045807 | positive regulation of endocytosis |
BP | IBA | GO:0048268 | clathrin coat assembly |
BP | IDA | GO:0048268 | clathrin coat assembly |
CC | IBA | GO:0005768 | endosome |
CC | IDA | GO:0005887 | integral component of plasma membrane |
CC | IBA | GO:0016021 | integral component of membrane |
CC | IEA | GO:0030659 | cytoplasmic vesicle membrane |
CC | IDA | GO:0031410 | cytoplasmic vesicle |
MF | IPI | GO:0005515 | protein binding |
MF | IBA | GO:0032051 | clathrin light chain binding |
MF | IDA | GO:0032051 | clathrin light chain binding |
MF | IEA | GO:0044877 | protein-containing complex binding |
Gene expression in normal tissue: CALY
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CALY
Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa04728 | Dopaminergic synapse - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CALY