CARNMT1


Summary: The protein encoded by this gene is a methyltransferase that converts carnosine to anserine, a dipeptide found abundantly in skeletal muscle. The encoded protein can methylate other dipeptides as well. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
carnosine N-methyltransferase 1MIM:616552Ensembl:ENSG00000156017HGNC:HGNC:23435PA1349293939q21.13

GO terms in CARNMT1


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0008757S-adenosylmethionine-dependent methyltransferase activity
MFIBAGO:0030735carnosine N-methyltransferase activity
MFIDAGO:0030735carnosine N-methyltransferase activity
MFTASGO:0030735carnosine N-methyltransferase activity
CCIBAGO:0005634nucleus
CCIDAGO:0005634nucleus
CCIBAGO:0005829cytosol
CCIDAGO:0005829cytosol
CCTASGO:0005829cytosol
BPTASGO:0006548histidine catabolic process
BPIEAGO:0032259methylation
BPIBAGO:0035498carnosine metabolic process
BPIDAGO:0035498carnosine metabolic process

Gene expression in normal tissue: CARNMT1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CARNMT1


DatabasePathway IDPathway Des.
kegghsa00340Histidine metabolism - Homo sapiens (human)
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-6788656Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism
reactomeR-HSA-70921Histidine catabolism
reactomeR-HSA-71291Metabolism of amino acids and derivatives

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD30917AAG2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CARNMT1

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