CATSPER1


Summary: Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
cation channel sperm associated 1MIM:606389Ensembl:ENSG00000175294HGNC:HGNC:17116PA3843811q13.1

GO terms in CATSPER1


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0007275multicellular organism development
BPIEAGO:0007283spermatogenesis
BPIEAGO:0030154cell differentiation
BPIEAGO:0030317flagellated sperm motility
BPIEAGO:0034765regulation of ion transmembrane transport
BPTASGO:0035036sperm-egg recognition
BPIEAGO:0070588calcium ion transmembrane transport
CCTASGO:0005886plasma membrane
CCIEAGO:0031514motile cilium
CCISSGO:0036128CatSper complex
MFIEAGO:0005227calcium activated cation channel activity
MFIPIGO:0005515protein binding

Gene expression in normal tissue: CATSPER1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CATSPER1


DatabasePathway IDPathway Des.
reactomeR-HSA-1187000Fertilization
reactomeR-HSA-1300642Sperm Motility And Taxes
reactomeR-HSA-1474165Reproduction

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CATSPER1

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