CCP110
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| centriolar coiled-coil protein 110 | MIM:609544 | Ensembl:ENSG00000103540 | HGNC:HGNC:24342 | PA166048960 | 16p12.3 |
Gene Categories:
TUMOR SUPPRESSORGO terms in CCP110
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| CC | IDA | GO:0005813 | centrosome |
| CC | IDA | GO:0005814 | centriole |
| CC | TAS | GO:0005829 | cytosol |
| CC | IEA | GO:0005929 | cilium |
| CC | IDA | GO:0032991 | protein-containing complex |
| BP | TAS | GO:0000086 | G2/M transition of mitotic cell cycle |
| BP | IMP | GO:0007099 | centriole replication |
| BP | TAS | GO:0010389 | regulation of G2/M transition of mitotic cell cycle |
| BP | TAS | GO:0016579 | protein deubiquitination |
| BP | ISS | GO:0032053 | ciliary basal body organization |
| BP | IMP | GO:0032465 | regulation of cytokinesis |
| BP | ISS | GO:0045724 | positive regulation of cilium assembly |
| BP | IDA | GO:0051298 | centrosome duplication |
| BP | IMP | GO:0051298 | centrosome duplication |
| BP | TAS | GO:0097711 | ciliary basal body-plasma membrane docking |
| BP | IMP | GO:1902018 | negative regulation of cilium assembly |
Gene expression in normal tissue: CCP110
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CCP110
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1640170 | Cell Cycle |
| reactome | R-HSA-1852241 | Organelle biogenesis and maintenance |
| reactome | R-HSA-2565942 | Regulation of PLK1 Activity at G2/M Transition |
| reactome | R-HSA-380259 | Loss of Nlp from mitotic centrosomes |
| reactome | R-HSA-380270 | Recruitment of mitotic centrosome proteins and complexes |
| reactome | R-HSA-380284 | Loss of proteins required for interphase microtubule organization from the centrosome |
| reactome | R-HSA-380287 | Centrosome maturation |
| reactome | R-HSA-380320 | Recruitment of NuMA to mitotic centrosomes |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-453274 | Mitotic G2-G2/M phases |
| reactome | R-HSA-5617833 | Cilium Assembly |
| reactome | R-HSA-5620912 | Anchoring of the basal body to the plasma membrane |
| reactome | R-HSA-5688426 | Deubiquitination |
| reactome | R-HSA-5689880 | Ub-specific processing proteases |
| reactome | R-HSA-597592 | Post-translational protein modification |
| reactome | R-HSA-68877 | Mitotic Prometaphase |
| reactome | R-HSA-68886 | M Phase |
| reactome | R-HSA-69275 | G2/M Transition |
| reactome | R-HSA-69278 | Cell Cycle, Mitotic |
| reactome | R-HSA-8854518 | AURKA Activation by TPX2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CCP110
CLASSFICATION
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