CECR2
Summary: This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| CECR2, histone acetyl-lysine reader | MIM:607576 | Ensembl:ENSG00000099954 | HGNC:HGNC:1840 | PA26383 | 22q11.1-q11.21 |
GO terms in CECR2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0090537 | CERF complex |
| BP | TAS | GO:0006309 | apoptotic DNA fragmentation |
| BP | NAS | GO:0007010 | cytoskeleton organization |
| BP | NAS | GO:0016192 | vesicle-mediated transport |
| BP | IEA | GO:0021915 | neural tube development |
| BP | IDA | GO:0043044 | ATP-dependent chromatin remodeling |
| BP | NAS | GO:0061640 | cytoskeleton-dependent cytokinesis |
| BP | IDA | GO:0097194 | execution phase of apoptosis |
Gene expression in normal tissue: CECR2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CECR2
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CECR2
CLASSFICATION
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