CLEC16A


Summary: This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
C-type lectin domain containing 16AMIM:611303Ensembl:ENSG00000038532HGNC:HGNC:29013PA16238234016p13.13

GO terms in CLEC16A


Term TypeEvidence TypeGO Term IDGO Des.
MFNDGO:0003674molecular_function
MFIBAGO:0017137Rab GTPase binding
CCIBAGO:0005770late endosome
CCIDAGO:0005794Golgi apparatus
CCIDAGO:0005829cytosol
CCIBAGO:0016021integral component of membrane
CCIDAGO:0031982vesicle
CCIBAGO:0036020endolysosome membrane
CCIEAGO:0036020endolysosome membrane
BPIEAGO:0006914autophagy
BPIBAGO:0008333endosome to lysosome transport
BPIMPGO:0009267cellular response to starvation
BPIBAGO:0016197endosomal transport
BPIEAGO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process
BPIBAGO:1901096regulation of autophagosome maturation
BPIMPGO:1901097negative regulation of autophagosome maturation
BPIEAGO:1901098positive regulation of autophagosome maturation
BPIEAGO:1901525negative regulation of mitophagy
BPIMPGO:1904263positive regulation of TORC1 signaling
BPIMPGO:1904766negative regulation of macroautophagy by TORC1 signaling

Gene expression in normal tissue: CLEC16A

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CLEC16A


DatabasePathway IDPathway Des.
wikipathwaysWP2877Vitamin D Receptor Pathway

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CLEC16A

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