DNALI1


Summary: This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
dynein axonemal light intermediate chain 1MIM:602135Ensembl:ENSG00000163879HGNC:HGNC:14353PA383811p34.3

GO terms in DNALI1


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005737cytoplasm
CCIDAGO:0005737cytoplasm
CCIDAGO:0005929cilium
CCIBAGO:0005930axoneme
CCIDAGO:0005930axoneme
CCIBAGO:0030175filopodium
CCIEAGO:0030286dynein complex
CCIDAGO:00977299+2 motile cilium
BPIBAGO:0036159inner dynein arm assembly
MFIEAGO:0003774motor activity
MFIPIGO:0005515protein binding
MFIBAGO:0045504dynein heavy chain binding

Gene expression in normal tissue: DNALI1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in DNALI1


DatabasePathway IDPathway Des.
kegghsa05016Huntington,s disease - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in DNALI1

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