DNALI1
Summary: This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| dynein axonemal light intermediate chain 1 | MIM:602135 | Ensembl:ENSG00000163879 | HGNC:HGNC:14353 | PA38381 | 1p34.3 |
GO terms in DNALI1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005929 | cilium |
| CC | IBA | GO:0005930 | axoneme |
| CC | IDA | GO:0005930 | axoneme |
| CC | IBA | GO:0030175 | filopodium |
| CC | IEA | GO:0030286 | dynein complex |
| CC | IDA | GO:0097729 | 9+2 motile cilium |
| BP | IBA | GO:0036159 | inner dynein arm assembly |
| MF | IEA | GO:0003774 | motor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0045504 | dynein heavy chain binding |
Gene expression in normal tissue: DNALI1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DNALI1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05016 | Huntington,s disease - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DNALI1
CLASSFICATION
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