EEF1B2
Summary: This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| eukaryotic translation elongation factor 1 beta 2 | MIM:600655 | Ensembl:ENSG00000114942 | HGNC:HGNC:3208 | PA27644 | 2q33.3 |
GO terms in EEF1B2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | NAS | GO:0006414 | translational elongation |
| BP | TAS | GO:0006414 | translational elongation |
| BP | IEA | GO:0045471 | response to ethanol |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005783 | endoplasmic reticulum |
| CC | TAS | GO:0005829 | cytosol |
| CC | NAS | GO:0005853 | eukaryotic translation elongation factor 1 complex |
| MF | NAS | GO:0003746 | translation elongation factor activity |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: EEF1B2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in EEF1B2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-156842 | Eukaryotic Translation Elongation |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-72766 | Translation |
| wikipathways | WP107 | Translation Factors |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in EEF1B2
CLASSFICATION
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