EGFL7
Summary: This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| EGF like domain multiple 7 | MIM:608582 | Ensembl:ENSG00000172889 | HGNC:HGNC:20594 | PA134928613 | 9q34.3 |
GO terms in EGFL7
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0005102 | signaling receptor binding |
| MF | IEA | GO:0005509 | calcium ion binding |
| BP | IEA | GO:0001525 | angiogenesis |
| BP | ISS | GO:0001568 | blood vessel development |
| BP | ISS | GO:0001570 | vasculogenesis |
| BP | IMP | GO:0001938 | positive regulation of endothelial cell proliferation |
| BP | IEA | GO:0007155 | cell adhesion |
| BP | IMP | GO:0045746 | negative regulation of Notch signaling pathway |
| BP | IBA | GO:0048856 | anatomical structure development |
| CC | IBA | GO:0005576 | extracellular region |
| CC | ISS | GO:0005576 | extracellular region |
| CC | IEA | GO:0005615 | extracellular space |
| CC | IBA | GO:0009986 | cell surface |
| CC | HDA | GO:0031012 | extracellular matrix |
Gene expression in normal tissue: EGFL7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in EGFL7
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in EGFL7
CLASSFICATION
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