EGFL7


Summary: This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
EGF like domain multiple 7MIM:608582Ensembl:ENSG00000172889HGNC:HGNC:20594PA1349286139q34.3

GO terms in EGFL7


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0005102signaling receptor binding
MFIEAGO:0005509calcium ion binding
BPIEAGO:0001525angiogenesis
BPISSGO:0001568blood vessel development
BPISSGO:0001570vasculogenesis
BPIMPGO:0001938positive regulation of endothelial cell proliferation
BPIEAGO:0007155cell adhesion
BPIMPGO:0045746negative regulation of Notch signaling pathway
BPIBAGO:0048856anatomical structure development
CCIBAGO:0005576extracellular region
CCISSGO:0005576extracellular region
CCIEAGO:0005615extracellular space
CCIBAGO:0009986cell surface
CCHDAGO:0031012extracellular matrix

Gene expression in normal tissue: EGFL7

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EGFL7


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EGFL7

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