GO terms in EIF3E


Term TypeEvidence TypeGO Term IDGO Des.
BPIMPGO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
BPIBAGO:0006413translational initiation
BPICGO:0006413translational initiation
BPIDAGO:0006413translational initiation
BPTASGO:0006413translational initiation
BPNASGO:0006446regulation of translational initiation
BPIPIGO:0045727positive regulation of translation
BPNASGO:0045947negative regulation of translational initiation
BPIPIGO:1902416positive regulation of mRNA binding
CCNASGO:0000785chromatin
CCIBAGO:0005634nucleus
CCIDAGO:0005634nucleus
CCNASGO:0005654nucleoplasm
CCIDAGO:0005737cytoplasm
CCIDAGO:0005829cytosol
CCTASGO:0005829cytosol
CCIBAGO:0005852eukaryotic translation initiation factor 3 complex
CCIDAGO:0005852eukaryotic translation initiation factor 3 complex
CCNASGO:0005852eukaryotic translation initiation factor 3 complex
CCHDAGO:0016020membrane
CCIDAGO:0016604nuclear body
CCIDAGO:0016605PML body
CCHDAGO:0070062extracellular exosome
MFHDAGO:0003723RNA binding
MFIBAGO:0003743translation initiation factor activity
MFICGO:0003743translation initiation factor activity
MFICGO:0003743translation initiation factor activity
MFIDAGO:0003743translation initiation factor activity
MFIPIGO:0005515protein binding
MFHDAGO:0045296cadherin binding
MFIPIGO:0047485protein N-terminus binding

Gene expression in normal tissue: EIF3E

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EIF3E


DatabasePathway IDPathway Des.
kegghsa03013RNA transport - Homo sapiens (human)
kegghsa05160Hepatitis C - Homo sapiens (human)
pidhif2pathwayHIF-2-alpha transcription factor network
wikipathwaysWP107Translation Factors
reactomeR-HSA-156827L13a-mediated translational silencing of Ceruloplasmin expression
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-72613Eukaryotic Translation Initiation
reactomeR-HSA-72649Translation initiation complex formation
reactomeR-HSA-72662Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
reactomeR-HSA-72689Formation of a pool of free 40S subunits
reactomeR-HSA-72695Formation of the ternary complex, and subsequently, the 43S complex
reactomeR-HSA-72702Ribosomal scanning and start codon recognition
reactomeR-HSA-72706GTP hydrolysis and joining of the 60S ribosomal subunit
reactomeR-HSA-72737Cap-dependent Translation Initiation
reactomeR-HSA-72766Translation

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD68Paclitaxel1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EIF3E

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