ENOSF1
Summary: This gene can encode a mitochondrial enzyme that is thought to convert L-fuconate to 2-keto-3-deoxy-L-fuconate. This locus was originally identified as the source of antisense RNAs of the adjacent thymidylate synthase gene. Splice variants at this locus may contain an alternate 3' exon that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and may downregulate TS expression. [provided by RefSeq, Aug 2017].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| enolase superfamily member 1 | MIM:607427 | Ensembl:ENSG00000132199 | HGNC:HGNC:30365 | PA134897613 | 18p11.32 |
GO terms in ENOSF1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | ND | GO:0005575 | cellular_component |
| CC | IEA | GO:0005739 | mitochondrion |
| BP | IEA | GO:0009063 | cellular amino acid catabolic process |
| BP | IDA | GO:0044275 | cellular carbohydrate catabolic process |
| MF | IDA | GO:0000287 | magnesium ion binding |
| MF | IEA | GO:0016853 | isomerase activity |
| MF | IDA | GO:0050023 | L-fuconate dehydratase activity |
Gene expression in normal tissue: ENOSF1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ENOSF1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa00051 | Fructose and mannose metabolism - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ENOSF1
CLASSFICATION
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