FAM57B


Summary: This gene encodes a transmembrane protein, which may be a likely target of peroxisome proliferator-activated receptor gamma (PPAR-gamma). The product of the orthologous gene in mouse is related to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
family with sequence similarity 57 member BMIM:615175Ensembl:ENSG00000149926HGNC:HGNC:25295PA14267186216p11.2

GO terms in FAM57B


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0045599negative regulation of fat cell differentiation
BPIEAGO:0046513ceramide biosynthetic process
CCIEAGO:0000139Golgi membrane
CCIDAGO:0005783endoplasmic reticulum
CCIEAGO:0005789endoplasmic reticulum membrane
CCIEAGO:0016021integral component of membrane
MFIEAGO:0050291sphingosine N-acyltransferase activity

Gene expression in normal tissue: FAM57B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in FAM57B


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012
iGMDRD30917AAG1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FAM57B

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