FAM57B
Summary: This gene encodes a transmembrane protein, which may be a likely target of peroxisome proliferator-activated receptor gamma (PPAR-gamma). The product of the orthologous gene in mouse is related to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| family with sequence similarity 57 member B | MIM:615175 | Ensembl:ENSG00000149926 | HGNC:HGNC:25295 | PA142671862 | 16p11.2 |
GO terms in FAM57B
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0045599 | negative regulation of fat cell differentiation |
| BP | IEA | GO:0046513 | ceramide biosynthetic process |
| CC | IEA | GO:0000139 | Golgi membrane |
| CC | IDA | GO:0005783 | endoplasmic reticulum |
| CC | IEA | GO:0005789 | endoplasmic reticulum membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| MF | IEA | GO:0050291 | sphingosine N-acyltransferase activity |
Gene expression in normal tissue: FAM57B
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FAM57B
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in FAM57B
CLASSFICATION
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