FILIP1
Summary: This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| filamin A interacting protein 1 | MIM:607307 | Ensembl:ENSG00000118407 | HGNC:HGNC:21015 | PA134992638 | 6q14.1 |
GO terms in FILIP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005730 | nucleolus |
| CC | IEA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | IBA | GO:0015629 | actin cytoskeleton |
| CC | IDA | GO:0015629 | actin cytoskeleton |
Gene expression in normal tissue: FILIP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FILIP1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in FILIP1
CLASSFICATION
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