FMNL3


Summary: The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
formin like 3MIM:616288Ensembl:ENSG00000161791HGNC:HGNC:23698PA13499232812q13.12

GO terms in FMNL3


Term TypeEvidence TypeGO Term IDGO Des.
CCIDAGO:0005737cytoplasm
CCIDAGO:0005794Golgi apparatus
CCIDAGO:0005829cytosol
CCTASGO:0005829cytosol
CCIDAGO:0005886plasma membrane
CCIDAGO:0043231intracellular membrane-bounded organelle
BPIEAGO:0001525angiogenesis
BPIMPGO:0007010cytoskeleton organization
BPIMPGO:0008360regulation of cell shape
BPIMPGO:0016477cell migration
BPIEAGO:0030036actin cytoskeleton organization
MFIEAGO:0003779actin binding
MFIEAGO:0017048Rho GTPase binding
MFISSGO:0032794GTPase activating protein binding

Gene expression in normal tissue: FMNL3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in FMNL3


DatabasePathway IDPathway Des.
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-194315Signaling by Rho GTPases
reactomeR-HSA-195258RHO GTPase Effectors
reactomeR-HSA-5663220RHO GTPases Activate Formins

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD68Paclitaxel1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FMNL3

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