FOXN3


Summary: This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
forkhead box N3MIM:602628Ensembl:ENSG00000053254HGNC:HGNC:1928PA2646014q31.3-q32.11

GO terms in FOXN3


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0006351transcription, DNA-templated
BPIEAGO:0006357regulation of transcription by RNA polymerase II
BPIGIGO:0007095mitotic G2 DNA damage checkpoint
BPIDAGO:0045892negative regulation of transcription, DNA-templated
BPIEAGO:0097094craniofacial suture morphogenesis
CCICGO:0005634nucleus
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISMGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIPIGO:0005515protein binding
MFIPIGO:0008022protein C-terminus binding

Gene expression in normal tissue: FOXN3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in FOXN3


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FOXN3

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