GDAP1
Summary: This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
ganglioside induced differentiation associated protein 1 | MIM:606598 | Ensembl:ENSG00000104381 | HGNC:HGNC:15968 | PA28626 | 8q21.11 |
GO terms in GDAP1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IBA | GO:0000266 | mitochondrial fission |
BP | IDA | GO:0000266 | mitochondrial fission |
BP | IBA | GO:0006626 | protein targeting to mitochondrion |
BP | IMP | GO:0006626 | protein targeting to mitochondrion |
BP | IBA | GO:0007005 | mitochondrion organization |
BP | IBA | GO:0008053 | mitochondrial fusion |
BP | IMP | GO:0008053 | mitochondrial fusion |
BP | IEA | GO:0032526 | response to retinoic acid |
BP | IEA | GO:0071305 | cellular response to vitamin D |
CC | HDA | GO:0005634 | nucleus |
CC | IBA | GO:0005739 | mitochondrion |
CC | IDA | GO:0005739 | mitochondrion |
CC | IDA | GO:0005829 | cytosol |
CC | HDA | GO:0016020 | membrane |
CC | IBA | GO:0031307 | integral component of mitochondrial outer membrane |
CC | IDA | GO:0031307 | integral component of mitochondrial outer membrane |
Gene expression in normal tissue: GDAP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GDAP1
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GDAP1