GDPD5


Summary: Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
glycerophosphodiester phosphodiesterase domain containing 5MIM:609632Ensembl:ENSG00000158555HGNC:HGNC:28804PA14267174311q13.4-q13.5

Gene Categories:

TUMOR SUPPRESSOR

GO terms in GDPD5


Term TypeEvidence TypeGO Term IDGO Des.
CCIEAGO:0016021integral component of membrane
CCIEAGO:0030426growth cone
CCIEAGO:0043025neuronal cell body
CCIEAGO:0097038perinuclear endoplasmic reticulum
BPIEAGO:0006629lipid metabolic process
BPIEAGO:0021522spinal cord motor neuron differentiation
BPIEAGO:0021895cerebral cortex neuron differentiation
BPIEAGO:0031175neuron projection development
BPIEAGO:0045666positive regulation of neuron differentiation
BPIEAGO:0045746negative regulation of Notch signaling pathway
BPIEAGO:0045787positive regulation of cell cycle
BPIEAGO:0048505regulation of timing of cell differentiation
MFIPIGO:0005515protein binding
MFIEAGO:0008889glycerophosphodiester phosphodiesterase activity
MFIEAGO:0047389glycerophosphocholine phosphodiesterase activity

Gene expression in normal tissue: GDPD5

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GDPD5


DatabasePathway IDPathway Des.
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-1483255PI Metabolism
reactomeR-HSA-1483257Phospholipid metabolism
reactomeR-HSA-556833Metabolism of lipids
reactomeR-HSA-6814848Glycerophospholipid catabolism

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD68Paclitaxel1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GDPD5

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