GPC2


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
glypican 2Ensembl:ENSG00000213420HGNC:HGNC:4450PA288317q22.1

Gene Categories:

DRUGGABLE GENOME

GO terms in GPC2


Term TypeEvidence TypeGO Term IDGO Des.
CCIEAGO:0005615extracellular space
CCIDAGO:0005783endoplasmic reticulum
CCTASGO:0005796Golgi lumen
CCTASGO:0005886plasma membrane
CCTASGO:0043202lysosomal lumen
CCIEAGO:0046658anchored component of plasma membrane
CCIEAGO:0062023collagen-containing extracellular matrix
BPTASGO:0001523retinoid metabolic process
BPTASGO:0006024glycosaminoglycan biosynthetic process
BPTASGO:0006027glycosaminoglycan catabolic process
BPIEAGO:0007224smoothened signaling pathway
BPIEAGO:0009966regulation of signal transduction
BPIEAGO:0030182neuron differentiation
MFIPIGO:0005515protein binding

Gene expression in normal tissue: GPC2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GPC2


DatabasePathway IDPathway Des.
pidglypican_2pathwayGlypican 2 network
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-1630316Glycosaminoglycan metabolism
reactomeR-HSA-1630316Glycosaminoglycan metabolism
reactomeR-HSA-1638091Heparan sulfate/heparin (HS-GAG) metabolism
reactomeR-HSA-1638091Heparan sulfate/heparin (HS-GAG) metabolism
reactomeR-HSA-1643685Disease
reactomeR-HSA-1793185Chondroitin sulfate/dermatan sulfate metabolism
reactomeR-HSA-196854Metabolism of vitamins and cofactors
reactomeR-HSA-1971475A tetrasaccharide linker sequence is required for GAG synthesis
reactomeR-HSA-2022928HS-GAG biosynthesis
reactomeR-HSA-2022928HS-GAG biosynthesis
reactomeR-HSA-2024096HS-GAG degradation
reactomeR-HSA-2187338Visual phototransduction
reactomeR-HSA-3560782Diseases associated with glycosaminoglycan metabolism
reactomeR-HSA-3560783Defective B4GALT7 causes EDS, progeroid type
reactomeR-HSA-3560801Defective B3GAT3 causes JDSSDHD
reactomeR-HSA-3656237Defective EXT2 causes exostoses 2
reactomeR-HSA-3656253Defective EXT1 causes exostoses 1, TRPS2 and CHDS
reactomeR-HSA-372790Signaling by GPCR
reactomeR-HSA-3781865Diseases of glycosylation
reactomeR-HSA-388396GPCR downstream signalling
reactomeR-HSA-418594G alpha (i) signalling events
reactomeR-HSA-4420332Defective B3GALT6 causes EDSP2 and SEMDJL1
reactomeR-HSA-6806667Metabolism of fat-soluble vitamins
reactomeR-HSA-71387Metabolism of carbohydrates
reactomeR-HSA-71387Metabolism of carbohydrates
reactomeR-HSA-975634Retinoid metabolism and transport

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GPC2

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