GRIPAP1
Summary: This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function. [provided by RefSeq, Aug 2013].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| GRIP1 associated protein 1 | MIM:300408 | Ensembl:ENSG00000068400 | HGNC:HGNC:18706 | PA38650 | Xp11.23 |
GO terms in GRIPAP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ND | GO:0003674 | molecular_function |
| MF | IPI | GO:0005515 | protein binding |
| BP | ND | GO:0008150 | biological_process |
| BP | IEA | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane |
| BP | IEA | GO:1905244 | regulation of modification of synaptic structure |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005829 | cytosol |
| CC | IEA | GO:0030054 | cell junction |
| CC | IEA | GO:0030424 | axon |
| CC | IEA | GO:0030425 | dendrite |
| CC | IEA | GO:0031901 | early endosome membrane |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | IEA | GO:0055038 | recycling endosome membrane |
| CC | HDA | GO:0072562 | blood microparticle |
| CC | IEA | GO:0098837 | postsynaptic recycling endosome |
Gene expression in normal tissue: GRIPAP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GRIPAP1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GRIPAP1
CLASSFICATION
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