GTPBP1


Summary: This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
GTP binding protein 1MIM:602245Ensembl:ENSG00000100226HGNC:HGNC:4669PA2905722q13.1

GO terms in GTPBP1


Term TypeEvidence TypeGO Term IDGO Des.
MFHDAGO:0003723RNA binding
MFIBAGO:0003746translation elongation factor activity
MFISSGO:0003924GTPase activity
MFIEAGO:0005525GTP binding
CCISSGO:0000177cytoplasmic exosome (RNase complex)
CCISSGO:0005829cytosol
CCHDAGO:0016020membrane
BPIBAGO:0006414translational elongation
BPTASGO:0006955immune response
BPTASGO:0007165signal transduction
BPISSGO:0046039GTP metabolic process
BPISSGO:0061014positive regulation of mRNA catabolic process

Gene expression in normal tissue: GTPBP1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GTPBP1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GTPBP1

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