HECA
Summary: This gene encodes the homolog of the Drosophila headcase protein, a highly basic, cytoplasmic protein that regulates the re-entry of imaginal cells into the mitotic cycle during adult morphogenesis. In Drosophila, the encoded protein also inhibits terminal branching of neighboring cells during tracheal development. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| hdc homolog, cell cycle regulator | MIM:607977 | Ensembl:ENSG00000112406 | HGNC:HGNC:21041 | PA134977625 | 6q24.1 |
Gene Categories:
TUMOR SUPPRESSORGO terms in HECA
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | HDA | GO:0016020 | membrane |
| BP | NAS | GO:0030323 | respiratory tube development |
| BP | IDA | GO:0045930 | negative regulation of mitotic cell cycle |
| BP | IMP | GO:0045930 | negative regulation of mitotic cell cycle |
| MF | ND | GO:0003674 | molecular_function |
Gene expression in normal tissue: HECA
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HECA
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HECA
CLASSFICATION
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