IMMP2L


Summary: This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
inner mitochondrial membrane peptidase subunit 2MIM:605977Ensembl:ENSG00000184903HGNC:HGNC:14598PA1348872587q31.1

Gene Categories:

PROTEASEDRUGGABLE GENOME

GO terms in IMMP2L


Term TypeEvidence TypeGO Term IDGO Des.
MFISSGO:0008233peptidase activity
MFIEAGO:0008236serine-type peptidase activity
BPIEAGO:0001541ovarian follicle development
BPIBAGO:0006627protein processing involved in protein targeting to mitochondrion
BPISSGO:0006627protein processing involved in protein targeting to mitochondrion
BPIEAGO:0006801superoxide metabolic process
BPIEAGO:0006974cellular response to DNA damage stimulus
BPIEAGO:0007283spermatogenesis
BPIEAGO:0007420brain development
BPIEAGO:0008015blood circulation
BPIEAGO:0022904respiratory electron transport chain
BPIEAGO:0030728ovulation
BPIBAGO:0033108mitochondrial respiratory chain complex assembly
BPIEAGO:0061300cerebellum vasculature development
CCIEAGO:0016021integral component of membrane
CCIBAGO:0042720mitochondrial inner membrane peptidase complex
CCISSGO:0042720mitochondrial inner membrane peptidase complex

Gene expression in normal tissue: IMMP2L

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in IMMP2L


DatabasePathway IDPathway Des.
kegghsa03060Protein export - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in IMMP2L

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