KDM4D
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| lysine demethylase 4D | MIM:609766 | Ensembl:ENSG00000186280 | HGNC:HGNC:25498 | PA164721552 | 11q21 |
GO terms in KDM4D
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IBA | GO:0035097 | histone methyltransferase complex |
| CC | IDA | GO:0035861 | site of double-strand break |
| CC | HDA | GO:0072562 | blood microparticle |
| BP | IMP | GO:0000724 | double-strand break repair via homologous recombination |
| BP | IMP | GO:0001932 | regulation of protein phosphorylation |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | IDA | GO:0033169 | histone H3-K9 demethylation |
| BP | IMP | GO:0035563 | positive regulation of chromatin binding |
| BP | IEA | GO:0055114 | oxidation-reduction process |
| BP | IMP | GO:0071479 | cellular response to ionizing radiation |
| BP | IMP | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining |
| MF | IBA | GO:0001078 | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | IBA | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| MF | IBA | GO:0003682 | chromatin binding |
| MF | IBA | GO:0032452 | histone demethylase activity |
| MF | TAS | GO:0032452 | histone demethylase activity |
| MF | IBA | GO:0032454 | histone demethylase activity (H3-K9 specific) |
| MF | IDA | GO:0032454 | histone demethylase activity (H3-K9 specific) |
| MF | IBA | GO:0035064 | methylated histone binding |
| MF | IEA | GO:0046872 | metal ion binding |
| MF | IEA | GO:0051213 | dioxygenase activity |
| MF | IBA | GO:0051864 | histone demethylase activity (H3-K36 specific) |
Gene expression in normal tissue: KDM4D
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in KDM4D
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-3214842 | HDMs demethylate histones |
| reactome | R-HSA-3247509 | Chromatin modifying enzymes |
| reactome | R-HSA-4839726 | Chromatin organization |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in KDM4D
CLASSFICATION
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