KIAA1324


Summary: Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
KIAA1324MIM:611298Ensembl:ENSG00000116299HGNC:HGNC:29618PA1426716071p13.3

GO terms in KIAA1324


Term TypeEvidence TypeGO Term IDGO Des.
BPIMPGO:0000045autophagosome assembly
BPIMPGO:0009267cellular response to starvation
BPIMPGO:0044090positive regulation of vacuole organization
BPIMPGO:2000786positive regulation of autophagosome assembly
CCIDAGO:0005764lysosome
CCIEAGO:0005765lysosomal membrane
CCIDAGO:0005770late endosome
CCIDAGO:0005802trans-Golgi network
CCIDAGO:0005886plasma membrane
CCIDAGO:0005887integral component of plasma membrane
CCIEAGO:0031902late endosome membrane
CCHDAGO:0070062extracellular exosome
MFHDAGO:0003723RNA binding

Gene expression in normal tissue: KIAA1324

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in KIAA1324


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD399Selumetinib1
iGMDRD68Paclitaxel1
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KIAA1324

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