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KLHDC8A

Summary: This gene encodes a kelch domain-containing protein which is upregulated in cancer. Upregulated expression of the encoded protein may provide an alternative pathway for tumors to maintain aggressiveness in the absence of epidermal growth factor receptor dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
kelch domain containing 8A	MIM:614503	Ensembl:ENSG00000162873	HGNC:HGNC:25573	PA142671583	1q32.1

GO terms in KLHDC8A

Term Type	Evidence Type	GO Term ID	GO Des.
BP	IEA	GO:0016567	protein ubiquitination

Gene expression in normal tissue: KLHDC8A

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in KLHDC8A

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD309	17AAG	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KLHDC8A

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CLASSFICATION

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