KLHDC8A
Summary: This gene encodes a kelch domain-containing protein which is upregulated in cancer. Upregulated expression of the encoded protein may provide an alternative pathway for tumors to maintain aggressiveness in the absence of epidermal growth factor receptor dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
kelch domain containing 8A | MIM:614503 | Ensembl:ENSG00000162873 | HGNC:HGNC:25573 | PA142671583 | 1q32.1 |
Gene expression in normal tissue: KLHDC8A
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in KLHDC8A
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in KLHDC8A