LRP10
Summary: This gene encodes a low density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. [provided by RefSeq, Jul 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| LDL receptor related protein 10 | MIM:609921 | Ensembl:ENSG00000197324 | HGNC:HGNC:14553 | PA38383 | 14q11.2 |
GO terms in LRP10
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005041 | low-density lipoprotein particle receptor activity |
| CC | IEA | GO:0005905 | clathrin-coated pit |
| CC | HDA | GO:0016020 | membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| BP | IEA | GO:0006629 | lipid metabolic process |
| BP | IEA | GO:0006869 | lipid transport |
| BP | IEA | GO:0006898 | receptor-mediated endocytosis |
| BP | IEA | GO:0048839 | inner ear development |
Gene expression in normal tissue: LRP10
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LRP10
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-196854 | Metabolism of vitamins and cofactors |
| reactome | R-HSA-2187338 | Visual phototransduction |
| reactome | R-HSA-372790 | Signaling by GPCR |
| reactome | R-HSA-388396 | GPCR downstream signalling |
| reactome | R-HSA-418594 | G alpha (i) signalling events |
| reactome | R-HSA-6806667 | Metabolism of fat-soluble vitamins |
| reactome | R-HSA-975634 | Retinoid metabolism and transport |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LRP10
CLASSFICATION
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