LRRC4
Summary: This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| leucine rich repeat containing 4 | MIM:610486 | Ensembl:ENSG00000128594 | HGNC:HGNC:15586 | PA30463 | 7q32.1 |
GO terms in LRRC4
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| BP | IEA | GO:0050807 | regulation of synapse organization |
| BP | IEA | GO:0097119 | postsynaptic density protein 95 clustering |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0030054 | cell junction |
| CC | IEA | GO:0043197 | dendritic spine |
| CC | IEA | GO:0045211 | postsynaptic membrane |
| CC | IEA | GO:0060076 | excitatory synapse |
Gene expression in normal tissue: LRRC4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LRRC4
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04360 | Axon guidance - Homo sapiens (human) |
| kegg | hsa04514 | Cell adhesion molecules (CAMs) - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LRRC4
CLASSFICATION
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