MFSD10
Summary: This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein likely functions in efflux of organic anions, including the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| major facilitator superfamily domain containing 10 | MIM:610977 | Ensembl:ENSG00000109736 | HGNC:HGNC:16894 | PA162395840 | 4p16.3 |
GO terms in MFSD10
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0005215 | transporter activity |
| MF | TAS | GO:0008493 | tetracycline transmembrane transporter activity |
| MF | IDA | GO:0008514 | organic anion transmembrane transporter activity |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | IEA | GO:0015904 | tetracycline transport |
| BP | IDA | GO:0043252 | sodium-independent organic anion transport |
| BP | IEA | GO:0055085 | transmembrane transport |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IDA | GO:0030659 | cytoplasmic vesicle membrane |
| CC | IBA | GO:0031526 | brush border membrane |
Gene expression in normal tissue: MFSD10
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MFSD10
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MFSD10
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.