MOGAT3


Summary: Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
monoacylglycerol O-acyltransferase 3MIM:610184Ensembl:ENSG00000106384HGNC:HGNC:23249PA1349592387q22.1

GO terms in MOGAT3


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0006071glycerol metabolic process
BPIEAGO:0019432triglyceride biosynthetic process
BPTASGO:0019432triglyceride biosynthetic process
CCTASGO:0005789endoplasmic reticulum membrane
CCIEAGO:0016021integral component of membrane
MFTASGO:00038462-acylglycerol O-acyltransferase activity
MFIEAGO:0004144diacylglycerol O-acyltransferase activity

Gene expression in normal tissue: MOGAT3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MOGAT3


DatabasePathway IDPathway Des.
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-556833Metabolism of lipids
reactomeR-HSA-75109Triglyceride biosynthesis
reactomeR-HSA-8979227Triglyceride metabolism
wikipathwaysWP325Triacylglyceride Synthesis
kegghsa00561Glycerolipid metabolism - Homo sapiens (human)
kegghsa04975Fat digestion and absorption - Homo sapiens (human)
humancycTRIGLSYN-PWYtriacylglycerol biosynthesis

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD30917AAG1
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MOGAT3

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