GO terms in MTHFD2L


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0004477methenyltetrahydrofolate cyclohydrolase activity
MFTASGO:0004477methenyltetrahydrofolate cyclohydrolase activity
MFIBAGO:0004487methylenetetrahydrofolate dehydrogenase (NAD+) activity
MFTASGO:0004487methylenetetrahydrofolate dehydrogenase (NAD+) activity
MFIBAGO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity
CCIEAGO:0005743mitochondrial inner membrane
CCTASGO:0005759mitochondrial matrix
CCIBAGO:0005829cytosol
BPIEAGO:0000105histidine biosynthetic process
BPIEAGO:0006164purine nucleotide biosynthetic process
BPIBAGO:0006730one-carbon metabolic process
BPIEAGO:0009086methionine biosynthetic process
BPIEAGO:000925610-formyltetrahydrofolate metabolic process
BPIBAGO:0035999tetrahydrofolate interconversion
BPIEAGO:0035999tetrahydrofolate interconversion
BPIBAGO:0046653tetrahydrofolate metabolic process
BPTASGO:0046655folic acid metabolic process
BPIEAGO:0055114oxidation-reduction process

Gene expression in normal tissue: MTHFD2L

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MTHFD2L


DatabasePathway IDPathway Des.
wikipathwaysWP2525Trans-sulfuration and one carbon metabolism
kegghsa00670One carbon pool by folate - Homo sapiens (human)
humancycPWY-2201folate transformations I
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-196757Metabolism of folate and pterines
reactomeR-HSA-196849Metabolism of water-soluble vitamins and cofactors
reactomeR-HSA-196854Metabolism of vitamins and cofactors

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD30917AAG1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MTHFD2L

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