NAP1L4


Summary: This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
nucleosome assembly protein 1 like 4MIM:601651Ensembl:ENSG00000205531HGNC:HGNC:7640PA3144211p15.4

GO terms in NAP1L4


Term TypeEvidence TypeGO Term IDGO Des.
BPIDAGO:0006334nucleosome assembly
CCIDAGO:0005634nucleus
CCIDAGO:0005737cytoplasm
MFHDAGO:0003723RNA binding
MFIPIGO:0005515protein binding
MFIDAGO:0031491nucleosome binding
MFTASGO:0051082unfolded protein binding

Gene expression in normal tissue: NAP1L4

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in NAP1L4


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NAP1L4

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