NEK10
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| NIMA related kinase 10 | Ensembl:ENSG00000163491 | HGNC:HGNC:18592 | PA38594 | 3p24.1 |
GO terms in NEK10
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0004672 | protein kinase activity |
| MF | IEA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0046872 | metal ion binding |
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | IDA | GO:0031954 | positive regulation of protein autophosphorylation |
| BP | IMP | GO:0043406 | positive regulation of MAP kinase activity |
| BP | IMP | GO:0070372 | regulation of ERK1 and ERK2 cascade |
| BP | IMP | GO:1902749 | regulation of cell cycle G2/M phase transition |
| CC | IDA | GO:1902911 | protein kinase complex |
Gene expression in normal tissue: NEK10
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NEK10
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD427 | ABT737 | 6 |
| iGMDRD289 | Parthenolide | 1 |
| iGMDRD318 | PAC-1 | 3 |
| iGMDRD474 | Avrainvillamide | 1 |
| iGMDRD298 | L-685458 | 3 |
| iGMDRD148 | Pifithrin-mu | 3 |
| iGMDRD579 | PF750 | 1 |
| iGMDRD883 | CIL55A | 3 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD188 | Piperlongumine | 1 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD577 | BIX01294 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NEK10
CLASSFICATION
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