PALM


Summary: This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
paralemminMIM:608134Ensembl:ENSG00000099864HGNC:HGNC:8594PA3292319p13.3

GO terms in PALM


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0005515protein binding
MFIEAGO:0031750D3 dopamine receptor binding
CCIDAGO:0005634nucleus
CCIBAGO:0005886plasma membrane
CCIDAGO:0005886plasma membrane
CCIEAGO:0014069postsynaptic density
CCIEAGO:0016323basolateral plasma membrane
CCIEAGO:0016327apicolateral plasma membrane
CCIEAGO:0030424axon
CCTASGO:0031235intrinsic component of the cytoplasmic side of the plasma membrane
CCTASGO:0031410cytoplasmic vesicle
CCIDAGO:0031527filopodium membrane
CCIEAGO:0032591dendritic spine membrane
CCIDAGO:0043231intracellular membrane-bounded organelle
BPIEAGO:0007010cytoskeleton organization
BPIEAGO:0007193adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
BPIBAGO:0007194negative regulation of adenylate cyclase activity
BPIDAGO:0007194negative regulation of adenylate cyclase activity
BPIEAGO:0008360regulation of cell shape
BPIBAGO:0023052signaling
BPIBAGO:0051491positive regulation of filopodium assembly
BPIDAGO:0051491positive regulation of filopodium assembly
BPIEAGO:0060074synapse maturation
BPIDAGO:0060160negative regulation of dopamine receptor signaling pathway
BPIEAGO:0071257cellular response to electrical stimulus
BPIEAGO:0072659protein localization to plasma membrane

Gene expression in normal tissue: PALM

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PALM


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PALM

​​​​